Topic 21 Measurement and data processing HL

21.1 TMS as the reference standard 

​Applications and skills:
Explanation of the use of tetramethylsilane  (TMS) as the reference standard.

---

21.1 High resolution 1H NMR

Understandings:
In a high resolution 1H NMR spectrum, single peaks present in low resolution can split into further clusters of peaks.
Guidance:
Students should be able to interpret the following from 1H NMR spectra: number of peaks, area under each peak, chemical shift and splitting patterns. Treatment of spin-spin coupling constants will not be assessed but students should be familiar with singlets, doublets, triplets and quartets.
​High resolution 1H NMR should be covered.

---

21.1 Determine the structure of a compound using analytic techniques. 

Applications and skills:
Deduction of the structure of a compound given information from a range of analytical characterization  techniques (X-ray crystallography,  IR, 1H NMR and MS).

---